1
F HNE were similar in the HFD+VEH and HFD+NDEA groups, and both were significantly higher than in the LFD+VEH and LFD +NDEA groups (P < 0.01). We did not detect significant inter-group differences with respect to MDA (Fig 3), protein carbonylation, or IL-1b, TNF-a, and IL-6 immunoreactivities (data not shown).NDEA-Mediated Increases in Pro-Ceramide Gene ExpressionWe investigated the potential role
1
F HNE were similar in the HFD+VEH and HFD+NDEA groups, and both were significantly higher than in the LFD+VEH and LFD +NDEA groups (P < 0.01). We did not detect significant inter-group differences with respect to MDA (Fig 3), protein carbonylation, or IL-1b, TNF-a, and IL-6 immunoreactivities (data not shown).NDEA-Mediated Increases in Pro-Ceramide Gene ExpressionWe investigated the potential role